Thursday, September 28, 2017

Prophylactic negative pressure wound therapy may help cut down surgical wound infections after cesarean


Prophylactic negative pressure wound therapy (NPWT) at cesarean delivery may reduce the surgical site infections (SSI) and overall wound complications says the results of a systematic review and meta-analysis published ahead of print in American journal of obstetrics and gynecology.

Morbidly obese women have a very high rate of SSIs and readmission to hospitals.
The researchers conducted a literature review and included RCTs and observational studies comparing surgical outcome between prophylactic negative pressure wound closure and standard cesarean wound closure.  

The investigators were mainly looking at difference in SSI because of NPWT besides other minor outcomes like composite wound complications, wound gaping, hematoma, endometritis and readmission to the hospital.

Six RCTs and three cohort study met the inclusion criteria. It was seen that women with NPWT faced a 55% lower risk of SSI as compared to women with standard dressing (pooled RR 0.45; 95% CI 0.31- 0.66). The Number Need to Treat (NNT) was 17.

Women with NPWT also had a 22 lower risk of composite wound complications, while the other minor outcomes were comparable in both the groups.

The authors concluded that although the studies were heterogenous, use of NPWT decreases the SSIs after  cesarean, larger clinical trials are awaited to fully understand the impact of the intervention.


For more news visit Facebook and Twitter





2 comments:

  1. This comment has been removed by the author.

    ReplyDelete
  2. I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
    liver already present. I started on antiviral medications which
    reduced the viral load initially. After a couple of years the virus
    became resistant. I started on HEPATITIS B Herbal treatment from
    ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
    treatment totally reversed the virus. I did another blood test after
    the 6 months long treatment and tested negative to the virus. Amazing
    treatment! This treatment is a breakthrough for all HBV carriers.

    ReplyDelete