Monday, August 28, 2017

Danish Society of Obstetrics and Gynecology recommends against vaginal seeding in Cesarean births

www.stayathomemum.com.au
The potential risks associated with practice of vaginal seeding (VS) in Cesarean Delivery outweighs the hypothetical benefits and consequently we do not recommend it at present says the national recommendations released by Danish Society of Obstetrics and Gynaecology at the national meeting on 19 January 2017.

The recommendation along with a commentary was published online 22 AUG 2017 in British Journal of Obstetrics and Gynecology.

“We could not identify any other national or international society that had systematically investigated the clinical approach to VS,” write Thor Haahr, MD, PhD, from the Department of Obstetrics and Gynaecology at the Institute for Clinical Medicine, Aarhus University Hospital, Skejby, Denmark.

The recommendations are aimed at providing fellow obstetricians and midwives with the basic information about VS so that it can be discussed with couples and families opting for it.

The recommendations state that:

Maternity wards should not take part in screening, guiding or encouraging women for Vaginal Seeding.

Vaginal seeding is contraindicated in infants born before 37 weeks, born to mothers who meet national criteria for group B streptococci(GBS) prophylaxis during delivery, situations in which the cesarean section is done to prevent vertical transmission of infection such as—primary vaginal herpes infection, HIV infection with HIV-RNA >50 copies/ml and any other situations in which the VS will cause potential harm to the fetus.

Parents who still wish to perform VS, can do so provided “it does not interfere with or delay other procedures.” They should be informed about insufficient evidence in favor of any potential benefit and should be provided with patient information booklet. They should also be educated about signs of infection in neonates should any infection occurs after the procedure.

Interest in VS sparked after Dominguez-Bello and colleagues published the results of their pilot study in 2016 stating that Neonatal colonization can be partially restored in cesarean born babies by VS.  Several other studies have since followed involving VS which stress the importance of more research and publications on this topic.


Although, the risk associated with VS is very low, the immediate concern after VS is early onset neonatal sepsis (EOS) with Escherichia coli or GBS.

David A. Eschenbach, MD, from the Department of Obstetrics and Gynecology, University of Washington, Seattle raised several questions in his accompanying commentary that need to be addressed before VS becomes a routine practice.

His major concern was our current inability to identify that which vaginal bacteria/gut bacteria will produce potential benefit while minimizing the harm. Choosing between ‘harmful’ and ‘helpful’ bacteria is expensive procedure and it is here the cost -benefit analysis comes in.

"We simply are too far behind in knowledge to start this practice without heeding the Society's recommendations," he concluded.

The authors suggest that clinicians whose patients want to adopt the practice should be told about the risk involved and other ways of that have an effect on neonatal colonization, including early skin-to-skin contact, breast-feeding, and diet during pregnancy.

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