Video worth watching: Easy taking pills to replace painful injections.

A new engineered pill technology developed by Rani Therapeutics in collaboration with InCube Labs, a multi-disciplinary life sciences R&D lab based in Silicon Valley will replace painful injections with painless,easy to swallow pills.

Globally millions of patients suffer from conditions that require painful injections, sometimes twice or thrice a day. All major biologics can only currently be administered via intramuscular or subcutaneous routes. These injections affect quality of life, and as a result, patient compliance can also become an issue.

The ‘Rani Pill’ enables biological drugs and proteins to be taken orally which otherwise would be destroyed in the stomach.  The pills safely deliver the drugs in intestine, where the outer coating is dissolved and needles made of sugar are released which inject the drug in the walls of intestines.  

The pill is made of FDA approves ingestible and injectable materials. It is currently being tested for insulin and biologics. It works for most drugs - Including small molecules, therapeutic peptides, proteins, antibodies and nucleotides.

The company is currently conducting pre-clinical studies and have shown more than 50% bioavailability.