Thursday, January 17, 2019

Osteoporosis drug Romosozumab receives marketing approval in Japan


Monoclonal antibody romosozumab gains first-ever marketing approval in Japan for the treatment of osteoporosis in patients at high risk of fracture announced Amgen and UCB in a joint press release. The drug will be known as Evenity in Japan and would be developed by Amgen Astellas BioPharma K.K.–a joint venture between Amgen and Astellas Pharma Inc., headquartered in Tokyo.


Romosozumab has a dual effect on the bone– it works by binding and inhibiting the activity of the protein sclerostin which increases bone formation and decreases bone breakdown.

Japanese people have the longest life expectancy in the world and with that comes the burden of osteoporotic fractures. In Japan, the osteoporotic fracture is the leading cause of disability that requires long term nursing home care.

"The approval of EVENITY in Japan is a significant milestone that reinforces our commitment to bringing effective treatments to the millions of patients who suffer from osteoporosis," said David M. Reese, M.D., executive vice president of Research and Development at Amgen in a news release.

"A patient with a prior osteoporotic fracture is twice as likely to suffer another fracture if left undiagnosed and without appropriate treatment. With this approval, physicians in Japan now have a new medicine to help patients reduce their risk of fracture."

The approval is based on results of two phase 3 clinical trials– FRAME and BRIDGE. The FRActure study in postmenopausal woMen with ostEoporosis (FRAME), included 7,180 postmenopausal women with osteoporosis. The women received romosozumab 210 mg s.c. or placebo once monthly for 12 months, followed by denosumab 60 mg s.c. once every 6 months in both groups for 12 months. The drug significantly increased spine and hip BMD and reduced vertebral and clinical fracture risk.

The BRIDGE study (placeBo-contRolled study evaluating the efficacy anD safety of romosozumab in treatinG mEn with osteoporosis) involved 245 men with osteoporosis (163 romosozumab, 82 placebo) randomized 2:1 to receive either 210 mg romosozumab or placebo subcutaneously once monthly for 12 months. Men on Romosozumab showed a significant bone mineral density (BMD) gains at the lumbar spine, total hip and femoral neck compared to placebo at six and 12 months.

The approval is also significant because FDA rejected Amgen’s initial marketing application for Romosozumab in the US because of cardiovascular side effects of the drug in ARCH trial. The drug is also under regulatory review in Europe.

The Japanese Pharmaceuticals and Medical Devices Agency undertook a thorough review of the safety profile of EVENITY, including the cardiovascular safety findings in the ARCH trial.

Toshio Matsumoto, M.D., Ph.D., emeritus professor of Tokushima University and the advisor of the university's Fujii Memorial Institute of Medical Sciences said in the press release, "Physicians have been waiting for a new therapeutic option. I have great hope that the approval of EVENITY will help reduce the fracture risk for patients in Japan."

"Patients with a prior fracture face the risk of having another fracture and particularly stand to benefit from the option of a new bone-forming agent," he further added.

Meanwhile, During the second review cycle, the US Food and Drug Administration (FDA) Bone, Reproductive, and Urologic Drugs Advisory Committee (BRUDAC) recently voted in favor of approving Amgen and UCB’s romosozumab (EVENITY) In the US for the treatment of postmenopausal women with osteoporosis at high risk for fracture. The committee indicated that the drug benefits for treatment of postmenopausal osteoporosis outweigh its risk.





54 comments:

  1. Hello everyone i Am williams pater and i am from USA i am here to give my testimony about an herbal doctor called Dr,olu I was heartbroken because i had very small penis,not nice to satisfy a woman, i have been in so many relationship, but cut off because of my situation, i have used so many product which doctors prescribe for me, but could not offer me the help i searched for. i saw some few comments on the internet about this specialist called Dr,OLU and decided to email him on his email i saw on the internet,(drolusolutionhome@gmail.com ) so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal product for Penis Enlargement, Within three weeks of me use it, i began to feel the enlargement, " and now it just 4 weeks of using his products my penis is about 8 inches longer, and i had to settle thing out with my ex girlfriend , i was surprised when she said that she is satisfied with my performance in bed and i now have a large penis.thanks to DR OLU for is herbal product. you can also reach him with emsil drolusolutionhome@gmail.com though is..number WHATASPP him today on this number [ +2348140654426 ]

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  4. My boyfriend and I met three years ago on herpes dating site so we discovered we are +ve from the beginning of our relationship, that we both had genital herpes. My first outbreak was the ABSOLUTE worst experience, I was so sick. We suffered for one year plus, had constant outbreaks and then finally we decided to both respectively take Dr Utu African Traditional Herbs as advised by friends. His herb is Not much bitter or sour taste.
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    ReplyDelete
    Replies
    1. God bless Dr.CHUKWU MADU for his wonderful work in my life, my name is Helen from USA, I was diagnosed of HERPES since 2016 and it has affected my life i was
      taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr CHUKWU MADU HERBALHOME how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS delivery company. I took the medicine as prescribed by him and 11 days later i tested negative for HERPES, Dr.CHUKWU MADU truly you are great,It's Good for herpes patient to please read my testimony becuase People think herpes is really a minor skin irritation,herpes has a long term effects on health and The stigma attached to this virus by ignorant people is ridiculous. do you need his help also? Why don't you contact him through his email (dr.chukwumaduherbalhome@gmail.com) or call him on +234703
      0936239, DOCTOR CHUKWU MADU CAN AS WELL CURE THE FOLLOWING DISEASE:- 1. HIV/AIDS 2. HERPES 3. CANCER 4. ALS 5. Hepatitis B AND C 6. Diabetes 7. Athrux, 8. hydrophobia 9.hpv 10 pregnancy spell and bring back your ex back 11 scabies 12. STD. 13.Kidney stone?

      Delete
  5. I got diagnosed with HPV, i have be dealing with this mess for the past 8yrs. On till i got review online about natural cure people testifies how they got cured with natural treatment. And i order the treatment, after taking it for two weeks i totally got cured with herbal treatment. I'm recommending you diagnosis with HPV should get this treatment via; princetesskarachi@gmail .com , lifecentre@live.com

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  7. Hello everyone i Am williams pater and i am from USA i am here to give my testimony about an herbal doctor called Dr,olu I was heartbroken because i had very small penis,not nice to satisfy a woman, i have been in so many relationship, but cut off because of my situation, i have used so many product which doctors prescribe for me, but could not offer me the help i searched for. i saw some few comments on the internet about this specialist called Dr,OLU and decided to email him on his email i saw on the internet,(drolusolutionhome@gmail.com ) so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal product for Penis Enlargement, Within three weeks of me use it, i began to feel the enlargement, " and now it just 4 weeks of using his products my penis is about 8 inches longer, and i had to settle thing out with my ex girlfriend , i was surprised when she said that she is satisfied with my performance in bed and i now have a large penis.thanks to DR OLU for is herbal product. you can also reach him with emsil  drolusolutionhome@gmail.com though is..number WHATASPP him today on this number [ +2348140654426 ]   














































    Hello everyone i Am williams pater and i am from USA i am here to give my testimony about an herbal doctor called Dr,olu I was heartbroken because i had very small penis,not nice to satisfy a woman, i have been in so many relationship, but cut off because of my situation, i have used so many product which doctors prescribe for me, but could not offer me the help i searched for. i saw some few comments on the internet about this specialist called Dr,OLU and decided to email him on his email i saw on the internet,(drolusolutionhome@gmail.com ) so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal product for Penis Enlargement, Within three weeks of me use it, i began to feel the enlargement, " and now it just 4 weeks of using his products my penis is about 8 inches longer, and i had to settle thing out with my ex girlfriend , i was surprised when she said that she is satisfied with my performance in bed and i now have a large penis.thanks to DR OLU for is herbal product. you can also reach him with emsil  drolusolutionhome@gmail.com though is..number WHATASPP him today on this number [ +2348140654426 ]   



















    ReplyDelete
  8. Am so happy to share this testimony thank you Dr Oduku i never believed i will be herpes negative again despite all i passed through Dr Oduku you are truly sent by God and you can also place your order for Dr Oduku roots and herbs medicine email odukuherbalremediess@gmail.com or what-app number +2347067706774.

    ReplyDelete
  9. Hello everyone i am Mudaf Kyle from MALARIA , i am here to give my testimony about a great Best Herbal Penis Enlargement Medicine    called Dr OLU, I was heartbroken and disappointed because i had very small penis, not big enough to satisfy or pregnant a woman, i have been in so many relationship, but cut off because of my small penis situation, i have used so many product,drugs,vaccines,herbs which doctors prescribe for me, but none could offer me the help i searched for. one faithful day i saw some few comments on the internet about how this great specialist called Dr OLU has been helping men enlarge their penis size ,pregnant woman and last longer in bed and i decided to email him on his email i saw on the internet,(drolusolutionhome@gmail.com) or you can also WhatasApp him  number +2348140654426so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words and steps to follow which i did with his herbal pills for Penis Enlargement, Within 1 week of it, i began to feel the enlargement of my penis, " and now it just 1 weeks of using his products my penis is about 10.5 inches longer in erection , and i had to settle out with my Ex girlfriend Stephanie, i was surprised when she opened her mouth and said that i almost killed her and she is satisfied with my sex and i have got a very Big penis now.Am so happy, thanks to Dr OLU I also learn that Dr OLU also help with
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    ReplyDelete
  10. Natural herbs have cured so many illness that drugs and injection cant
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    ReplyDelete
  11. I will like to share this great testimony of drsalatosolutiontemple@gmail.com or website https://drsalatosolutionte0.wixsite.com/drsalato that helped me to save my marriage by increasing my Penis size and i now know that penis size really matters in a relationship or marriage. I got married to my wife about 2 month after
    we met on a photo studio, we lived happily for the first 5 months of our marriage until i and my wife start having quarrels at home because i couldn't satisfy her on bed with my small penis. Actually my penis was very small, it measured about 3.5 inch long on erection and i am 35 years old ,man. My wife said it was forbidden by the women of this world.. Sometimes i will return from work without finding my wife at home and whenever i call or ask her where she was, she will always snub at me and sometimes just tell me to go get a larger dick. All this continued for a long time and it hurt me so much that i was at the edge of breaking up on the marriage till when i read about a Herbal doctor called DR. SALATO online. I never thought i could smile and be in a
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    i am so thankful to DR SALATO for helping me. you can call OR whatsapp him +2348103629945 THANKS

    ReplyDelete
  12. QUICK RELIABLE CURE, Am so glad expressing my profound gratitude to a man that is so concerned about other people's well being. I was suffering from (HERPES SIMPLEX VIRUS) over 4 years, i have spent thousands of dollars in buying expensive drugs and visiting several hospitals in different countries, i was really in severe pain "until" one glorious morning, i read about Doctor Razor on the internet on how he had helped and cured so many people suffering from HERPES 1&2, HPV, CANCER, HIV/AIDS, ALZHEIMER, FIBROID, ENLARGED PROSTATE, HEMORRHOIDS' PILE and HEART DISEASE ETC. So i contacted him through this Email: drrazorherbalhome@gmail.com and i shared my problems with him, he gave me the healing procedure and i followed them. 18 days later he told me to go for a medical test, behold the result was negative, now am (HERPES SIMPLEX VIRUS)  Negative. I just want to use this platform to thank Doctor Razor for curing me from that deadly virus and also for exposing his herbal cure to the world, please you can as well contact him at drrazorherbalhome@gmail.com (or) Whatsapp/Call him +2349065420442 for solutions to your health problems

    ReplyDelete
  13. God bless Dr.CHUKWU MADU for his wonderful work in my life, my name is Helen from USA, I was diagnosed of HERPES since 2016 and it has affected my life i was
    taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr CHUKWU MADU HERBALHOME how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS delivery company. I took the medicine as prescribed by him and 11 days later i tested negative for HERPES, Dr.CHUKWU MADU truly you are great,It's Good for herpes patient to please read my testimony becuase People think herpes is really a minor skin irritation,herpes has a long term effects on health and The stigma attached to this virus by ignorant people is ridiculous. do you need his help also? Why don't you contact him through his email (dr.chukwumaduherbalhome@gmail.com) or call him on +234703
    0936239, DOCTOR CHUKWU MADU CAN AS WELL CURE THE FOLLOWING DISEASE:- 1. HIV/AIDS 2. HERPES 3. CANCER 4. ALS 5. Hepatitis B AND C 6. Diabetes 7. Athrux, 8. hydrophobia 9.hpv 10 pregnancy spell and bring back your ex back 11 scabies 12. STD. 13.Kidney stone?

    ReplyDelete
  14. My Name is Dr AZIBA, Herbal Remedy Product is 100% guarantee for Penis Enlargement growth and Thickness you can Contact Me via Email Priestazibasolutioncenter@gmail.com For Best natural male enhancement Product with 100% guaranteed results. I prepare top Herbal selling male enhancement product with herbal formula and no side-effects, MY WhatsApp Number is +2348100368288

    ReplyDelete
  15. My Name is Dr AZIBA, Herbal Remedy Product is 100% guarantee for Penis Enlargement growth and Thickness you can Contact Me via Email Priestazibasolutioncenter@gmail.com For Best natural male enhancement Product with 100% guaranteed results. I prepare top Herbal selling male enhancement product with herbal formula and no side-effects, MY WhatsApp Number is +2348100368288

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  16. My Name is Dr AZIBA, Herbal Remedy Product is 100% guarantee for Penis Enlargement growth and Thickness you can Contact Me via Email Priestazibasolutioncenter@gmail.com For Best natural male enhancement Product with 100% guaranteed results. I prepare top Herbal selling male enhancement product with herbal formula and no side-effects, MY WhatsApp Number is +2348100368288

    ReplyDelete
  17. Greetings everyone.

    i am very happy to share this little awesome testimony about Dr OKISIN a great herbal doctor who help me enlarge my penis size.3.2 cm to 8.3 cm longer with his herbal cream mixture, my girlfriend is now so amazed with the autonomous size of my penis , if you you are also in need of help on how to enlarge your penis to become bigger and stronger I advIce you to contact Dr OKISIN on his email (dr.okisinsolutiontemple@gmail.com) ) or contact him on whatsapp number +2348149508633 because he is one of the best herbal doctor that i can only show you up to, if your penis is 4.2 cm and want to get it reach 9.2 cm within three weeks i recommend Dr OKISIN he is also specialized on  breast and boobs enlargement i will advise you to contact him for help   DR OKISIN whatsapp number +2348149508633...........

    ReplyDelete

  18. I am very happy to share this little awesome testimony about Dr Aizonofe a great herbal doctor who help me enlarge my penis size.3.2 cm to 8.3 cm longer with his herbal cream mixture, my girlfriend is now so amazed with the autonomous size of my penis , if you you are also in need of help on how to enlarge your penis to become bigger and stronger I advice you to contact Dr Aizonofe on his email (draizonofeherb@gmail.com )or contact him on whatsapp number +2348136785562, if your penis is 4.2 cm and want to get it reach 9.2 cm within two weeks i recommend Dr Aizonofe, just feel like promoting his Good work, Give him a try and thank me later.

    ReplyDelete
  19. My Sincere Gratitude to Dr Razor, I was infected with HERPES SIMPLEX VIRUS 2 November 13 2018, I went to many hospitals for cure but there was no solution, I was confused because the medical drugs has become my daily food, but i decided to sort after Natural Herbs. One day I sat beside the pool, Browsing and thinking where I could get a solution to end this my predicament. I saw a blog on how Dr Razor cured people with his herbal medicine, i did not believe but i just decided to give him a try, Visit Doctor's Razor's Website : https://drrazorherbalhome.wixsite.com/drrazorherbalhome .I contacted him and he prepare the herbs for me which i took, and he instructed me to go for check up, after the test i was confirmed herpes negative, i am so happy. If you have any problem or you are also infected with any disease, kindly contact him now with his Email: drrazorherbalhome@gmail.com or call +2349065420442This testimonial serves as an expression of my gratitude.
    He also have a herbal cure for COLD SORE,
    SHINGLES,
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    Contact him on this email: drrazorherbalhome@gmail.com , or call his cell phone number on +2349065420442

    ReplyDelete
  20. I have been suffering from (HERPES) Infection for the last 3 years and had several outbreaks as well as constant pain, especially in my knees. During the first year, I had faith in God that i would be healed someday.This disease started circulating all over my body and i have been taking treatment from my doctor, July 7 2019, i was searching on the internet if i could get any information concerning the prevention of this disease, on my search i saw a testimony of someone who has been healed from HERPES SIMPLEX-2 by this Man Dr Razor and she also gave the email address of this man, urged Researchers to visit his website : https://drrazorherbalhome.wixsite.com/drrazorherbalhome  and advise we should contact him for any sickness that he could be of help, So i wrote to Doctor Razor telling him about my (HERPES Virus) he told me not to worry that i was going to be cured!! hmm i never believed it, well after all the procedures and remedy given to me by this man, He gave me instruction to take it for 18 days, later on i started experiencing changes all over me as the Dr have earlier assured me. After The said 18 days, I went to my doctor to confirm if i have be finally healed behold it was TRUE, I was still very doubtful because i have heard that the virus is capable of hiding in the body undetected, i waited till this year 2020 before going for another medical test and it was still Negative. So friends my advise is if you have such sickness or any other at all, you can email Dr Razor on Email: drrazorherbalhome@gmail.com Sir i am indeed grateful for the help, i will forever recommend you to my friends!!! Whatsapp/Call this Herbalist Via +2349065420442

    ReplyDelete
  21. I was heartbroken because i had very small penis, not nice to satisfy a woman, i had so many relationship cut off because of my situation, i have used so many product which i found online but none could offer me the help i searched for. i saw some few comments about this specialist called Dr OKISIN and decided to email him at dr.okisinsolutiontemple@gmail.com, so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal pills for Penis Enlargement, Within 14days of it, i began to feel the enlargement of my penis, " and now it just 2 weeks of using his products my penis is about 9 inches longer and i am so happy, contact DR OKISIN now via email dr.okisinsolutiontemple@gmail.com  or his Whatsapp number +2348149508633. may God reward you for your good work.
    HE ALSO RENDER THE FOLLOWING ........1.  BRING YOUR EX BACK........... 2. LOTTERY SPELL......... 3. PREGNANCY SPELL ..........4. WEAK ERECTION ............5. POOR EJACULATION.............
    6. LOW SPERM COUNT.....................

    ReplyDelete

  22. I am very happy to share this little awesome testimony about Dr Aizonofe a great herbal doctor who help me enlarge my penis size.3.2 cm to 8.3 cm longer with his herbal cream mixture, my girlfriend is now so amazed with the autonomous size of my penis , if you you are also in need of help on how to enlarge your penis to become bigger and stronger I advice you to contact Dr Aizonofe on his email (draizonofeherb@gmail.com )or contact him on whatsapp number +2348136785562, if your penis is 4.2 cm and want to get it reach 9.2 cm within two weeks i recommend Dr Aizonofe, just feel like promoting his Good work, Give him a try and thank me later.

    ReplyDelete
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    ReplyDelete
  24. My Name is Dr AZIBA, Herbal Remedy Product is 100% guarantee for Penis Enlargement growth and Thickness you can Contact Me via Email Priestazibasolutioncenter@gmail.com For Best natural male enhancement Product with 100% guaranteed results. I prepare top Herbal selling male enhancement product with herbal formula and no side-effects And also for other Disease or virus such as HPV,HSV,HERPES,HEPATITIS, DIABETES,CANCER and lots More, Contact Me Via Email: Priestazibasolutioncenter@gmail.com and WhatsApp +2348100368288 Or website https://naturalherbsmedicine.webs.com/






































    ReplyDelete
  25. My Name is Dr AZIBA, Herbal Remedy Product is 100% guarantee for Penis Enlargement growth and Thickness you can Contact Me via Email Priestazibasolutioncenter@gmail.com For Best natural male enhancement Product with 100% guaranteed results. I prepare top Herbal selling male enhancement product with herbal formula and no side-effects And also for other Disease or virus such as HPV,HSV,HERPES,HEPATITIS, DIABETES,CANCER and lots More, Contact Me Via Email: Priestazibasolutioncenter@gmail.com and WhatsApp +2348100368288 Or website https://naturalherbsmedicine.webs.com/

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  26. I am very happy to share this little awesome testimony about Dr Okosun a great herbal doctor who help me enlarge my penis size.3.2 cm to 8.3 cm longer with his herbal mixture, my girlfriend is now so amazed with the autonomous size of my penis , if you you are also in need of help on how to enlarge your penis to become bigger and stronger I advice you to contact Dr Okosun on his email (drokosun12@gmail.com )or contact him on whatsapp number +2348136785562, if your penis is 4.2 cm and want to get it reach 9.2 cm within two weeks i recommend Dr Okosun just feel like promoting his Good work, Give him a try and thank me later.

    ReplyDelete
  27. Unbelievable..... Is like a dream but is real, @dr_ahonsi the real cure to all diseases, @dr_ahonsi cure my (HERPES SIMPLEX VIRUS) that was in my body for over 6 years, The story start like this, I contacted Herpes from my ex-husband, It was hell, i was in search of a cure for years, until a friend introduce me to @dr_ahonsi I thought he was a scam, but i gave him a try, he told me what to purchase to prepare the Herbal Medicine, so i buy all the required items, before 2 days he prepare the medicine and send it to me, i take the medicine for 3 weeks then i went  back for check up, the Doctor was even surprise to tell me that am cured, Thank you @dr_ahonsi for bringing happiness to my life, you can also contact him today if you have any disease, Email him :(drahonsi517@gmail.com) or whatsapp him:+2349046402730 for your complete cure

    ReplyDelete
  28. HOW DR AZIBA HELPED ME ENLARGE MY PENIS SIZE FROM 3.5 INCHES TO 11INCHES LONG AND 8.0 GROWTH  https://naturalherbsmedicine.webs.com/ (WhatsApp) +2348100368288
    I got married 2 years ago and it just seemed that there was no excitement in my sex life. My dysfunction to perform to the best of my abilities in bed made it harder for my wife and me to have a good time during sex. And i was having the feelings that she may decide to get a divorce one day. I knew something had to be done in order to improve my sex life and to save my marriage because my marriage was already falling apart, so when i was on my Facebook page i came across a story of how Dr Aziba helped him enlarged his penis to 8ins better.so i Immediately copied the Email address of the Dr and explained to him my problem,he gave me some simply instruction which i must follow and i did easily and my friends Today, i am the happiest man on Earth, All Thanks to Dr Aziba for saving my marriage and making me a real man today.i asked him about some purpular diseases like HERPES,HIV AIDS,HEPATITES,DIABETIS, CANCERS, WART, Get Ex back ,etc....... which are affecting most people he said there is no disease without a cure , he has it all...You can as well reach the Dr below for help on your problem, for he has the solution to all...
    Email:[ PRIESTAZIBASOLUTIONCENTER@GMAIL COM ]
    WhatsAPP DR [ +2348100368288 ]

    ReplyDelete
  29. droisemudiamenherbalhome@yahoo.com my dear readers around the globe, it is a great privilege to tell you about this great man who helped me over come the tragedy in my relationship, and how his herbal medicine help me too. My relationship became so complicated to a stage that I was scared of losing my wife to another, lasting long in bed was a problem and I knew deep down in my that my wife was not happy about it. Sometimes when I asked for sex the way she would act before the sex I noticed it was because I was not satisfying her, when she needed it more I hard already come and it was not the best. So I needed to find solution that was how I came in contact with DR OISE he really changed my sex life and ever since then life has been fun because my wife now love me more than she used to, all thanks to DR OISE for this great thing he did for me.. If you ever need help of any kind sickness like DIABETES.. HERPES.. you can visit DR OISE for solution droisemudiamenherbalhome@yahoo.com or https://m.facebook.com/Droisemudiamenherbalhome-112841510493268/?ref=bookmarkswhat's app +2348121847014

    ReplyDelete
  30. I was diagnosed of herpes 3 years, and ever since then i have been taking treatment to prevent outbreaks, burning and blisters, but there was no improvement until i came across testimonies of Dr. VOODOO on how he has been curing different people from different diseases all over the world, then i contacted him. After our conversation he sent me the medicine which i took according to his instructions for up to 2 weeks. After completing the medication i went back to my doctor for another test and the virus was all gone and i was completely cured, since then i have not had any signs of outbreak. I'm so filled with joy. With herbal medication Herpes Virus is 100% curable. I refer Dr VOODOO to everyone out there with the virus Email: voodoospelltemple66@gmail.com Add Dr voodoo on whatsApp +2348140120719

    ReplyDelete
  31. hello viewers i am very happy to share this testimony of DR SALATO who helped me to enlarge my penis size also save my marriage with his herbal medicine within two weeks of using his herbal medicine when i almost lost my marriage because i was having a very small penis,my wife always complain that i cannot satisfy her in bed the way she wanted because my penis was 2.5 inches long on erection and it was causing a lot problem between me and my wife also my wife wanted to divorce me because of the issue but my problem was solved when i was searching through the internet for a solution to my problem then i came across a testimony of one MR LUCKY from ITALY testifying on how DR SALATO enlarged his penis from 3 inches to 10 inches with his herbal cream .then i decided to give him a try by contacting him via email drsalatosolutiontemple@gmail.com and he replied and gave me some things to do,which i did and it was only 7 days of using his herbal medicine and my penis has increased to 5 inches.now it is two weeks and my penis size is now 10 inches and i now last longer in bed more than before and my wife enjoy me more than before.i am so thankful to Dr Salato for what he did in my life. If you are having problems with your penis enlargement then you can contact him on his email drsalatosolutiontemple@gmail.comwebsite https://drsalatosolutionte0.wixsite.com/drsalato also you can call/whatsapp him +2348103629945 THANKS

    ReplyDelete
  32. DR SALATO HERBAL MEDICINE FOR PENIS ENLARGEMENT drsalatosolutiontemple@gmail.com  or visit His website http://drsalatosolutionte0.wixsite.com/drsalato ,  you can call/whatsapp him via +2348103629945
     hello everyone here i am QUIN JACOB am medical doctor from UK but currently in NEW YORK i want to share a great testimony of how Dr SALATO herbal mixture cream saves me from shame and disgrace, my penis was a big problem to me as the size was really so embarrassing and discouraging, a 35 year old  grown man like me having 3.5 inches penis and to worsen it i don't last more than 10 minute  in bed it was really a thing of shame my wife was really tired of me because my sex life was very  very poor , she never enjoyed sex with me, i was always thinking and searching for a solutions everywhere until last one months ago when i saw a testimony of how Dr SALATO herbal mixture cream have been helping people around the globe,i saw one MR TIMOTHY  testifying of how Dr SALATO helped him enlarge his penis size from 4 to 8 inches so i decided to give him a try ,i visited his website link https://drsalatosolutionte0.wixsite.com/drsalato     we talked and he gave me steps to follow which i did and to my greatest surprise in less than two weeks of taking the herbal mixture cream my penis grow to 7 inches i couldn't believe my eyes and as i speak now my penis is now 9 inches long and i was amazed when my wife said i satisfy her so well in bed now all thanks to Dr SALATO  herbal mixture cream,i will forever be grateful To him i also learnt that Dr SALATO also have the herbal cure to problems like
    PENIS ENLARGEMENT
    ERECTILE DYSFUNCTION
    DIABETES type 1 and type 2
    HERPES GENITAL WART
    LOW SPERM COUNT
    WEAK ERECTION
    BREAST ENLARGEMENT
    PROSTATE CANCER
    HIV/AIDS
    SPELL OF ALL KINDS LIKE EX BACK,CANCEL DIVORCE,BREAK UP SPELL ,PREGNANCY SPELL,PROMOTION SPELL,JOB SPELL
    ALS
    HPV 123
    PILE
    ASTHMA
    HEART FAILURE
    PREMATURE EJACULATION
    HEPATITIS A,B,C AND MANY MORE
    so if you are suffering from any of these problems please do not hesitate to contact him now email drsalatosolutiontemple@gmail.com  or visit His website https://drsalatosolutionte0.wixsite.com/drsalato ,  you can call/whatsapp him via +2348103629945 THANKS 

    ReplyDelete
  33. I thought the physicians said there is no pills or another way for PENIS ENLARGEMENT !!! I am telling you today that Dr Aziba has the product for PENIS ENLARGEMENT and it worked perfectly for me from 3:0 to 8:95 and still counting. Contact Dr Aziba for help to Enlarge your penis via Email him via: Priestazibasolutioncenter@gmail.com and WhatsApp Him on +2348100368288

    ReplyDelete
  34. I am so happy to share this wonderful testimony thank you dr Godwin for the help you redeem to me I will be forever grateful now my ex love is back to me and everything's alright if you want your ex back if you are passing through similar problem whatsApp +2348088337602 you can also contact him on gmail drobaspellhome902@gmail.com  

    ReplyDelete
  35. i am very happy to share this little awesome testimony about Dr AZIBA a great herbal doctor who help me enlarge my penis size.3.2 cm to 8.3 cm longer with his herbal cream mixture, my girlfriend is now so amazed with the autonomous size of my penis. if you you are also in need of help on how to enlarge your penis to become bigger and stronger I advised you to contact Dr Aziba on his Email ( PRIESTAZIBASOLUTIONCENTER@GMAIL COM ) you or contact on whatsapp number +2348100368288 because he is one of the best herbal doctor that i can only show you up to, if your penis is 4.2 cm and want to get it reach 9.2 cm within three weeks Dr AZIBA is also specialized on breast and boobs enlargement i advise you to contact him for help DR AZIBA whatsapp number +2348100368288 .

    ReplyDelete
  36. i am very happy to share this little awesome testimony about Dr AZIBA a great herbal doctor who help me enlarge my penis size.3.2 cm to 8.3 cm longer with his herbal cream mixture, my girlfriend is now so amazed with the autonomous size of my penis. if you you are also in need of help on how to enlarge your penis to become bigger and stronger I advised you to contact Dr Aziba on his Email ( PRIESTAZIBASOLUTIONCENTER@GMAIL COM ) you or contact on whatsapp number +2348100368288 because he is one of the best herbal doctor that i can only show you up to, if your penis is 4.2 cm and want to get it reach 9.2 cm within three weeks Dr AZIBA is also specialized on breast and boobs enlargement i advise you to contact him for help DR AZIBA whatsapp number +2348100368288 .

    ReplyDelete
  37. I thought the physicians said there is no pills or another way for PENIS ENLARGEMENT !!! I

    am telling you today that Dr Aziba has the product for PENIS ENLARGEMENT and it worked

    perfectly for me from 3:0 to 8:95 and still counting. Contact Dr Aziba for help to Enlarge

    your penis via Email him via: Priestazibasolutioncenter@gmail.com 

    ReplyDelete
  38. I have found that this site is very informative, interesting and very well written. keep up the nice high quality writing Pap Smear Singapore

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  39. i am very happy to share this little awesome testimony about Dr AZIBA a great herbal doctor who help me enlarge my penis size.3.2 cm to 8.3 cm longer with his herbal cream mixture, my girlfriend is now so amazed with the autonomous size of my penis , if you you are also in need of help on how to enlarge your penis to become bigger and stronger I advice you to contact Dr Aziba on his email ( PRIESTAZIBASOLUTIONCENTER@GMAIL COM ) you or contact on whatsapp number +2348100368288 because he is one of the best herbal doctor that i can only show you up to, if your penis is 4.2 cm and want to get it reach 9.2 cm within three weeks Dr AZIBA is also specialized on breast and boobs enlargement i advise you to contact him for help DR AZIBA whatsapp number +2348100368288...........

    ReplyDelete
  40. i am very happy to share this little awesome testimony about Dr AZIBA a great herbal doctor who help me enlarge my penis size.3.2 cm to 8.3 cm longer with his herbal cream mixture, my girlfriend is now so amazed with the autonomous size of my penis , if you you are also in need of help on how to enlarge your penis to become bigger and stronger I advice you to contact Dr Aziba on his email ( PRIESTAZIBASOLUTIONCENTER@GMAIL COM ) you or contact on whatsapp number +2348100368288 because he is one of the best herbal doctor that i can only show you up to, if your penis is 4.2 cm and want to get it reach 9.2 cm within three weeks Dr AZIBA is also specialized on breast and boobs enlargement i advise you to contact him for help DR AZIBA whatsapp number +2348100368288...........

    ReplyDelete
  41. I want to thank Dr CHO-CHA for the herbal  medicine he gave to me and my daughter, i was suffering from Herpes when i gave birth to my daughter and that was how my daughter got the sickness indirect from me, but to God be the glory that i am heal with the herbal medicine that Dr CHO-CHA gave to me when i contacted him. i want to use this medium to tell everyone that the solution to our sickness has come, so i will like you to contact this great healer on his email address: chochaherbalarenaforhealing@gmail.com with him all your pains will be gone, i am really happy today that i and my daughter are cured of Herpes  we are now negative after the use of his medicine,my doctor confirm it. once more i say a big thank to you  Dr CHO-CHA for healing hands upon my life and my daughter, i say may God continue to bless you abundantly and give you more power to keep helping those that want your help in their lives. email him now he is waiting to receive you : chochaherbalarenaforhealing@gmail.com

    ReplyDelete
  42. Never give up in life they all say no cure to HSV 2 which is a big lie I have pass through many process also i never believe there is really cure to HERPES until I meet Dr Shaibu the doctor that have been helping many people for many years, I came across this doctor online when I was searching for cure online I found out about this man, and to my greatest surprise this man have the herbal medicine which I have been looking for years I explain my problem to him through the email I found on someone who testify about him also, Dr Shaibu write me a reply and explain how the process work so after ordering for the medicine I got it within 4 days and I took it according to the way Dr Shaibu instructed, I was so happy after two week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative that was the day I have the tears of joy you can also get in contact with my doctor through his email now drshaibuabacha@gmail.com or WhatsApp him +2349051727475. And He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

    ReplyDelete
  43. Never give up in life they all say no cure to HSV 2 which is a big lie I have pass through many process also i never believe there is really cure to HERPES until I meet Dr Shaibu the doctor that have been helping many people for many years, I came across this doctor online when I was searching for cure online I found out about this man, and to my greatest surprise this man have the herbal medicine which I have been looking for years I explain my problem to him through the email I found on someone who testify about him also, Dr Shaibu write me a reply and explain how the process work so after ordering for the medicine I got it within 4 days and I took it according to the way Dr Shaibu instructed, I was so happy after two week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative that was the day I have the tears of joy you can also get in contact with my doctor through his email now drshaibuabacha@gmail.com or WhatsApp him +2349051727475. And He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

    ReplyDelete
  44. HAVING A Long and Thicker PENIS gives you a 100% guarantee when meeting your girlfriend or wife and as well makes her respect you more as the real man for being able to satisfy her sexual needs. waste no more time, get in contact with Doctor Aziba for his herbal product to help you get the actual size deserved for your woman and make her happy like every other women out there, Doctor Aziba product is 100% Vegans and guarantee with no side effects Contact Doctor Aziba via whatsApp: +2348100368288 or mail him: PRIESTAZIBASOLUTIONCENTER@GMAIL.COM

    ReplyDelete

  45. I am so happy how Dr Voke cured me from Herpes virus and Hepatitis-b, since 4 year ago i was effected with herpes simplex virus 1 and hepatitis-b, and i have taken all manner of drugs prescribed to me by several doctors,but all my effort was wasted,i cried all day thinking on how i can be cured of this illness, i lost hope while i was looking for solution for my health,but one faithful day, i was searching the internet i came across several testimonies about Dr Voke, and how he has cure so many effected individual ,so i try and contact his email and asked him for solution about my herpes simplex virus 1 and he started the preparation to my cure,to my greatest surprise after two weeks, i was totally cure by his powerful herbal medicine,i never believe that i could be cured from this wicked disease until i met Dr voke i’m very grateful to you and i know your herbal medicine will save more millions of lives. his email Address doctorvoke@yahoo.com, Whatsapp phone number +1 (773) 349 2820.

    ReplyDelete
  46. I was diagnosed of herpes virus, I have tried all possible means to get cure but all my effort proved abortive, until a friend of mine introduced me to a herbal doctor called Dr Agaba, who prepare herbal medicine to cure all kind of diseases including herpes virus (Herpes), when i contacted this herbal doctor via email, he sent me herpes virus herbal medicine via courier service, when i received the herbal medicine he gave me step by step instructions on how to apply it, when i applied it as instructed i was totally cured from the virus within 3 weeks of usage. Contact this great herbal doctor today to get your cure. 
    Via Email: Dragabasolutionhome@gmail.com or WhatApp: +2349074536486

    ReplyDelete
  47. Hi viewers, I'm posting this Because i found lots of people having marriage problems which I also experienced. I recently found help from a man called Dr. Oselumen he did a great job that made my man fell back in love with me again after ten months of separation. I want you to know there are fake online spell Dr .s if someone out there needs help, can email this great spell caster, droselumen@gmail. com check or connect with him on WhatsApp +2348054265852. He will give you the best result.
    CONTACT HIM FOR ANY KIND OF HELP,MONEY SPELL,LOTTERY SPELL,PREGNANCY SPELL,DIVORCE SPELL,SPELL TO STOP COURT CASE AND WIN ANY COURT PROBLEM,DEATH SPELL,BUSINESS SPELL,HEALING SPELL,SPELL TO REMOVE BLACK MAGIC OUT FROM YOUR LIFE,FAMILY AND MARRIAGE PROBLEM.

    ReplyDelete
  48. Hi everyone, I am MAY WALTHER, I was going through some  websites and I found a man called Dr SALATO . I have been suffering from DIVORCES issues from  TWO different women concerning my 3.0 inches penis size. I have contacted so many  spell caster and herbal healer but none could solve my problem for me CINDY my 3rd wife was on the verge of divorcing me for another man just because of my inability to satisfy her on the bed .but i stayed positive and believe i could stop  her from divorcing me and make her stay. and behold i met Dr SALATO who helped me enlarge my penis through his herbal medicine cream . CINDY  and i are  happy together again and she was so happy the first night we had sex after using his cream for two weeks and i got 9 inches and 8.0 girth. Dr SALATO is such a nice and honest man who takes his patient happiness as his priority, he also helped me stop my Heart failure problem. Thanks to him and thanks to God for the gift given to him. If you have any problem whatsoever, contact him on this email: drsalatosolutiontemple@gmail.com  or website http://drsalatosolutionte0.wixsite.com/drsalato 
    Contact him for the following problems and see the great work of Dr SALATO
    SPELL
    (1)If you want your ex back.
    {2}If you want to be very successful
    (3)If you are searching for a job
    (4)You want to be promoted in your office.
    (5)You want women/men to run after you.
    (6)If you want a child.
    (7)You want to be rich.
    (8)you want to get Marriage Spells
    (9)Remove Sickness from your body Spells
    (10)Business spell
    (11)Lottery winning numbers
    (12)Bring Back Lost Love

    CURE
    PENIS ENLARGEMENT
    PREMATURE EJACULATION
    LOW SPERM COUNT
    ERECTILE DYSFUNCTION
    HIV/AIDS CURE
    HERPES CURE
    INFECTION CURE
    PILE
    STROKE
    HEART6 FAILURE
    CANCER
    REDUCING OF FATS AND BUMS
    ASTHMA and many more.......
    contact him on this email: drsalatosolutiontemple@gmail.com or website http://drsalatosolutionte0.wixsite.com/drsalato or whatsapp him directly on +2348103629945   

    ReplyDelete

  49. I would like to thank Ultimate Life Clinic for reversing my father's Amyotrophic Lateral Sclerosis (ALS). My father’s ALS condition was fast deteriorating before he started on the ALS Herbal medicine treatment from Ultimate Life Clinic. He was on the treatment for just 6 months and we never thought my father will recover so soon. He has gained some weight in the past months and he is able to walk with no support. You can reach them through there website www.ultimatelifeclinic.com

    ReplyDelete
  50. Are you having issues in your relationship, or finding it difficult to have a child of your own or are you the type having any diseases in your body. I will advice you to contact Dr. Abolo of Abolospell@gmail.com . The potency of his spell is so effective and can reunite broken relationship and can also make one get pregnant know matter the situation and not only that, he also has the power to cure all type of diseases within the period of 48hours.. Contact him today and thank me later.



    Contact details : Abolospell@gmail.com

    You can also send him a MSG on whatsapp directly via: +27743411428.

    ReplyDelete
  51. Technologistan is the popoular and most trustworthy resource for technology, telecom, business and auto news in Pakistan

    ReplyDelete