Tuesday, January 8, 2019

Minimally invasive transcervical radiofrequency ablation shows promising results for uterine fibroids


Ultrasound-guided transcervical radiofrequency ablation provides an effective, safe and minimally invasive alternative for the treatment of symptomatic uterine fibroids suggests the results of pivotal IDE trial published in the January issue of Obstetrics & Gynecology.

The prospective, longitudinal, multicenter Sonography-Guided Transcervical Fibroid Ablation (SONATA) trial evaluated Gynesonics's investigational Sonata system in the treatment of heavy menstrual bleeding (HMB) because of uterine leiomyomata.

The Sonata System combines real-time intrauterine ultrasound guidance with targeted radiofrequency ablation in an incisionless procedure to treat symptomatic uterine fibroids.

The trial enrolled 147 premenopausal women between age 25-50 years with HMB for at least three months, across 22 centers in the United States and Mexico. The size and number of fibroids varied between 1 to 5 cm diameters and 1-10 fibroids per woman respectively.

All women were followed for 12 months and results assessed in terms of relief from heavy menstrual blood loss, device-related complications, and surgical intervention rate.

Scott Chudnoff, Chief of OB/GYN at Stamford Hospital, Stamford CT a principal investigator in the SONATA trial, said in a press release, “The actual results achieved in the SONATA trial far exceed the required thresholds established by the FDA for the co-primary endpoints of reduction in menstrual bleeding and freedom from surgical reintervention for bleeding. These results, along with the impressive levels of patient satisfaction and rapid return to normal activity achieved, clearly demonstrate the potential for Sonata as a first line treatment for symptomatic fibroids.”

At the end of follow-up period of 12 months, 99% of patients did not require any additional surgical intervention for controlling HMB, 94% of patients reported relief from substantial blood loss with 60% reporting a 50% reduction in the amount of blood loss.

There was minimal surgical downtime with half of them returning to regular activity the next day of surgery, and 97% were satisfied with the procedure. No device-related complications were reported.
Procedure-related adverse events reported include fibroid sloughing (30.6%), cramping or pain (7.5%), leukorrhea (6.1%), and uncomplicated genitourinary infections (4.8%).

The results of the study earned FDA clearance for the SONATA system in August 2018. The results were also consistent with the previously published FAST-EU trial. Chris Owens, President and CEO stated.

 “Considering these two prospective, multicenter trials were comprised of several disparate patient populations across two continents and performed by a broad range of physician operators across various healthcare delivery systems, and clinical settings, the consistency of these results is remarkable. The reproducible results highlight the robustness of the Sonata platform design and its potential to become a new standard of care for fibroid treatment.”

Gynesonics funded the study, and lead author have received travel and lodging expenses and honoraria for speaking for Gynesonics. 

Here is a video showing SONATA system overview


33 comments:

  1. Fantastic ESP. IN infertile cases

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  2. My boyfriend and I met three years ago on herpes dating site so we discovered we are +ve from the beginning of our relationship, that we both had genital herpes. My first outbreak was the ABSOLUTE worst experience, I was so sick. We suffered for one year plus, had constant outbreaks and then finally we decided to both respectively take Dr Utu African Traditional Herbs as advised by friends. His herb is Not much bitter or sour taste.
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    1. God bless Dr.CHUKWU MADU for his wonderful work in my life, my name is Helen from USA, I was diagnosed of HERPES since 2016 and it has affected my life i was
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  8. i was 3 years ago diagnosed of fibroid and complicated Endometriosis. My medical condition was heart broken because it was causing my menstrual cramps,bloating before menstrual periods,lower abdominal pressure which result to heavy periods. I was subjected to different medications by my doctor for treatment such as Coenzyme Q10,ibuprofen, Danazol and many more. Despite my visit to several doctors my health wasn't getting better, all they could say was surgery. At the verge of giving up, I went to the internet to search for a treatment at least. But I found a cure instead. In the internet, I read a testimony of a lady who had Fibroid. She shared an e-mail address of the Doctor. Luckily everything seemed to be okay after I took the Herbal Medicine. I wish I could say that’s the end of it because I haven't had any symptoms since then.
    Do not expose yourself to more danger, use a herbal remedy that is safe and effective. If interested contact him via email address: Drgodstimehealinghome@gmail.com or WhatsApp +2349063469910

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  9. Thanks to Dr OSAGIE for helping me increase the size of my Penis. I have been married for 10 years and due to my small Penis I was unable to satisfy my wife and that made us childless and my wife planed to leave me I was really disappointed with myself and I was also having weak erection I thought all my hope was gone not until I saw a testimony on how the same Dr OSAGIE helped someone increase his Penis size. I was desperate to do anything to regain my sex life back and I contacted him and he promise to help me so he gave me a herbal mixture which i was using and after three days I began to experience changes. Well am writing this testimony is not only because he has helped me increase the size of my Penis, I can now satisfy my wife and my wife is three months pregnant. All thanks to Dr OSAGIE if you are having weak erection problem or small Penis size contact him with his email:drosagiesolutionhome5@gmail.com or whats app him +2348034778129.




    Thanks to Dr OSAGIE for helping me increase the size of my Penis. I have been married for 10 years and due to my small Penis I was unable to satisfy my wife and that made us childless and my wife planed to leave me I was really disappointed with myself and I was also having weak erection I thought all my hope was gone not until I saw a testimony on how the same Dr OSAGIE helped someone increase his Penis size. I was desperate to do anything to regain my sex life back and I contacted him and he promise to help me so he gave me a herbal mixture which i was using and after three days I began to experience changes. Well am writing this testimony is not only because he has helped me increase the size of my Penis, I can now satisfy my wife and my wife is three months pregnant. All thanks to Dr OSAGIE if you are having weak erection problem or small Penis size contact him with his email:drosagiesolutionhome5@gmail.com or whats app him +2348034778129.

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  11. QUICK RELIABLE CURE, Am so glad expressing my profound gratitude to a man that is so concerned about other people's well being. I was suffering from (HERPES SIMPLEX VIRUS) over 4 years, i have spent thousands of dollars in buying expensive drugs and visiting several hospitals in different countries, i was really in severe pain "until" one glorious morning, i read about Doctor Razor on the internet on how he had helped and cured so many people suffering from HERPES 1&2, HPV, CANCER, HIV/AIDS, ALZHEIMER, FIBROID, ENLARGED PROSTATE, HEMORRHOIDS' PILE and HEART DISEASE ETC. So i contacted him through this Email: drrazorherbalhome@gmail.com and i shared my problems with him, he gave me the healing procedure and i followed them. 18 days later he told me to go for a medical test, behold the result was negative, now am (HERPES SIMPLEX VIRUS)  Negative. I just want to use this platform to thank Doctor Razor for curing me from that deadly virus and also for exposing his herbal cure to the world, please you can as well contact him at drrazorherbalhome@gmail.com (or) Whatsapp/Call him +2349065420442 for solutions to your health problems

    ReplyDelete
  12. QUICK RELIABLE CURE, Am so glad expressing my profound gratitude to a man that is so concerned about other people's well being. I was suffering from (HERPES SIMPLEX VIRUS) over 4 years, i have spent thousands of dollars in buying expensive drugs and visiting several hospitals in different countries, i was really in severe pain "until" one glorious morning, i read about Doctor Razor on the internet on how he had helped and cured so many people suffering from HERPES 1&2, HPV, CANCER, HIV/AIDS, ALZHEIMER, FIBROID, ENLARGED PROSTATE, HEMORRHOIDS' PILE and HEART DISEASE ETC. So i contacted him through this Email: drrazorherbalhome@gmail.com and i shared my problems with him, he gave me the healing procedure and i followed them. 18 days later he told me to go for a medical test, behold the result was negative, now am (HERPES SIMPLEX VIRUS)  Negative. I just want to use this platform to thank Doctor Razor for curing me from that deadly virus and also for exposing his herbal cure to the world, please you can as well contact him at drrazorherbalhome@gmail.com (or) Whatsapp/Call him +2349065420442 for solutions to your health problems

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  13. HELLO everyone! Still don’t know the right words to express my Gratitude to dr. Omoru herbal formula...i was diagnosed with the HERPES VIRUS for the past 6 years, i was given so many health prescription and advice with no improvement, I totally lost hope, until i found many testimonies of how doctor Omoru herbal mixture has been saving lives in an online research Like anybody would do, i'm Glad to be completely cured and freed from this virus.., i advice any one that is living with HERPES virus should Contact doctor Omoru today, because he has the cure to this virus...contact him on email omoru81@gmail.com or whatsApp him on +2348180828544

    ReplyDelete
  14. God bless Dr.CHUKWU MADU for his wonderful work in my life, my name is Helen from USA, I was diagnosed of HERPES since 2016 and it has affected my life i was
    taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr CHUKWU MADU HERBALHOME how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS delivery company. I took the medicine as prescribed by him and 11 days later i tested negative for HERPES, Dr.CHUKWU MADU truly you are great,It's Good for herpes patient to please read my testimony becuase People think herpes is really a minor skin irritation,herpes has a long term effects on health and The stigma attached to this virus by ignorant people is ridiculous. do you need his help also? Why don't you contact him through his email (dr.chukwumaduherbalhome@gmail.com) or call him on +234703
    0936239, DOCTOR CHUKWU MADU CAN AS WELL CURE THE FOLLOWING DISEASE:- 1. HIV/AIDS 2. HERPES 3. CANCER 4. ALS 5. Hepatitis B AND C 6. Diabetes 7. Athrux, 8. hydrophobia 9.hpv 10 pregnancy spell and bring back your ex back 11 scabies 12. STD. 13.Kidney stone?

    ReplyDelete
  15. God bless Dr.CHUKWU MADU for his wonderful work in my life, my name is Helen from USA, I was diagnosed of HERPES since 2016 and it has affected my life i was
    taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr CHUKWU MADU HERBALHOME how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS delivery company. I took the medicine as prescribed by him and 11 days later i tested negative for HERPES, Dr.CHUKWU MADU truly you are great,It's Good for herpes patient to please read my testimony becuase People think herpes is really a minor skin irritation,herpes has a long term effects on health and The stigma attached to this virus by ignorant people is ridiculous. do you need his help also? Why don't you contact him through his email (dr.chukwumaduherbalhome@gmail.com) or call him on +234703
    0936239, DOCTOR CHUKWU MADU CAN AS WELL CURE THE FOLLOWING DISEASE:- 1. HIV/AIDS 2. HERPES 3. CANCER 4. ALS 5. Hepatitis B AND C 6. Diabetes 7. Athrux, 8. hydrophobia 9.hpv 10 pregnancy spell and bring back your ex back 11 scabies 12. STD. 13.Kidney stone?

    ReplyDelete
  16. My Sincere Gratitude to Dr Razor, I was infected with HERPES SIMPLEX VIRUS 2 November 13 2018, I went to many hospitals for cure but there was no solution, I was confused because the medical drugs has become my daily food, but i decided to sort after Natural Herbs. One day I sat beside the pool, Browsing and thinking where I could get a solution to end this my predicament. I saw a blog on how Dr Razor cured people with his herbal medicine, i did not believe but i just decided to give him a try, Visit Doctor's Razor's Website : https://drrazorherbalhome.wixsite.com/drrazorherbalhome .I contacted him and he prepare the herbs for me which i took, and he instructed me to go for check up, after the test i was confirmed herpes negative, i am so happy. If you have any problem or you are also infected with any disease, kindly contact him now with his Email: drrazorherbalhome@gmail.com or call +2349065420442This testimonial serves as an expression of my gratitude.
    He also have a herbal cure for COLD SORE,
    SHINGLES,
    CANCER(Cannabis Oil),
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    IMPOTENCE,
    BARENESS/INFERTILITY ..
    Contact him on this email: drrazorherbalhome@gmail.com , or call his cell phone number on +2349065420442

    ReplyDelete

  17. I came on the Internet i saw great testimony about DR Voke on how he was able to cure someone from HERPES, and any disease this person said great things about this man, and advice we contact him for any problem that DR Voke can be of help, well i decided to give him a try, he requested for my information which i sent to him, and he told me he was going to prepare for me a healing portion, which he wanted me to take for days, and after which i should go back to the hospital for check up, well after taking all the treatment sent to me by DR Voke i went back to the Hospital for check up, and now i have been confirmed HERPES Negative, friends you can reach Dr voke on any treatment for any Disease, reach him on _________________________________doctorvoke@gmail. com

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  19. Your article was very instructive and informative. I read articles for gaining knowledge and I like to write articles a lot. If you want, you can see how I have custom writing us here.

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  20. I want to thank Dr CHO-CHA for the herbal  medicine he gave to me and my daughter, i was suffering from Herpes when i gave birth to my daughter and that was how my daughter got the sickness indirect from me, but to God be the glory that i am heal with the herbal medicine that Dr CHO-CHA gave to me when i contacted him. i want to use this medium to tell everyone that the solution to our sickness has come, so i will like you to contact this great healer on his email address: chochaherbalarenaforhealing@gmail.com with him all your pains will be gone, i am really happy today that i and my daughter are cured of Herpes  we are now negative after the use of his medicine,my doctor confirm it. once more i say a big thank to you  Dr CHO-CHA for healing hands upon my life and my daughter, i say may God continue to bless you abundantly and give you more power to keep helping those that want your help in their lives. email him now he is waiting to receive you : chochaherbalarenaforhealing@gmail.com

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  21. I was having Herpes Simplex Virus then i came across a review of people saying that they got treated from Herpes Simplex Virus by Dr Voke., So i gave a try by contacting him through his email and explain my problem to him. He told me all the things I need to do and also give me instructions to take, which I followed properly. Before I knew what is happening after two weeks the HERPES SIMPLEX VIRUS that was in my body got vanished . so if you are also heart broken by any deadly diseases like HERPES HIV, shingles,low sperm count or bringing back your ex lover, this great man is extremely the best in which I have seen and applauds and if you also need a help, you can also email him via email (doctorvoke1@gmail.com) or Whatsapp him on:+1 (773) 349 2820

    ReplyDelete
  22. Natural herbs have cured so many illness that drugs and injection cant cure. I've seen the great importance of natural herbs and the wonderful work they have done in people's lives. i read people's testimonies online on how they were cured of herpes, HIV, cancer, lutos diabetics etc by Dr. ISHIAKU  herbal medicine, so i decided to contact the doctor, I was diagnosed with herpes for the past 6 month but Dr. ISHIAKU cured me with his herbs and i referred my aunt and her husband to him immediately because they were both suffering from hiv but to God be the glory, they were cured too .I know is hard to believe but am a living testimony. There is no harm trying herbs. He is also a spell caster, he cast spell to restore broken marriages and he cast good luck spells to prosper and excel in life. Contact Dr ISHIAKU on Whatsapp or call him +2348180828544 OR email him ISHIAKUHERBALCURE@GMAIL.COM

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  23. I have found that this site is very informative, interesting and very well written. keep up the nice high quality writing Water Warts

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  24. I was diagnosed of herpes virus, I have tried all possible means to get cure but all my effort proved abortive, until a friend of mine introduced me to a herbal doctor called Dr Agaba, who prepare herbal medicine to cure all kind of diseases including herpes virus (Herpes), when i contacted this herbal doctor via email, he sent me herpes virus herbal medicine via courier service, when i received the herbal medicine he gave me step by step instructions on how to apply it, when i applied it as instructed i was totally cured from the virus within 3 weeks of usage. Contact this great herbal doctor today to get your cure. 
    Via Email: Dragabasolutionhome@gmail.com or WhatApp: +2349074536486

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  26. this is real take it serious, who will believe that a herb can cure ten
    years HIV in my body, i never believe that this will work i have spend a
    lot when getting drugs from the hospital to keep me healthy, what i was
    waiting for is death because i was broke, one day i hard about this great
    man who is well know of HIV and cancer cure, i decided to email him,
    unknowingly to me that this will be the end of the HIV aids in my body, he
    prepare the herb for me, and give me instruction on how to take it, at the
    end of the two week, he told me to go to the hospital for a check up, and i
    went, surprisingly after the test the doctor confirm me negative, i thought
    it was a joke, i went to other hospital was also negative, then i took my
    friend who was also HIV positive to the Dr voodoo after the treatment she
    was also confirm negative . He also have the herb to cure cancer please i
    want every one with this virus to be free, that is why am dropping his
    email address, voodoospelltemple66@gmail.com i want you to email him he
    is a great man. the government is also interested in this Dr voodoo
    thank you for saving my life, and I promise I will always testify
    for your good work you can also add him on whatsApp
    +2348140120719

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  27. I would like to thank Ultimate Life Clinic for reversing my father's Amyotrophic Lateral Sclerosis (ALS). My father’s ALS condition was fast deteriorating before he started on the ALS Herbal medicine treatment from Ultimate Life Clinic. He was on the treatment for just 6 months and we never thought my father will recover so soon. He has gained some weight in the past months and he is able to walk with no support. You can reach them through there website www.ultimatelifeclinic.com

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