An
Endometrial Thickness(EMT) of less than 7.0 mm results in lowest livebirth
rates of about 22%, reports the results of a large retrospective, single-center
study involving 2827 women, published electronically in forthcoming issue of Journal
Reproductive BioMedicine Online.
These cohort of women underwent 3350 IVF cycles with fresh embryos over a period of 4
years.
Endometrial thickness
is still a part of standard cycle monitoring during IVF but lacks robust
evidence in its favor as a potential predictor of live births and success rate
of the cycle.
Endocrine
profile is being increasingly used in infertility practice to predict the
outcome of various ART techniques.
Multivariate
regression analysis showed that EMT was non-linearly associated with live birth
rates.
Thickness
between 7.0 mm and 9.0 mm resulted in about 30% live birth rate while thickness
less than 7.0 mm was associated with only 22% live birth rate and a decrease in
neonatal birth weight.
The results
of the study reaffirm the value of measuring EMT as a prognostic tool for predicting
live birth rates and neonatal weights in women undergoing IVF with fresh embryo
transfer along with endocrine profile in late follicular phase.
Media courtesy Journal of Human Reproductive Sciences
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