Monday, January 29, 2018

EMT helps predicts the potential success of IVF cycle and neonatal birth-weight


An Endometrial Thickness(EMT) of less than 7.0 mm results in lowest livebirth rates of about 22%, reports the results of a large retrospective, single-center study involving 2827 women, published electronically in forthcoming issue of Journal Reproductive BioMedicine Online. These cohort of women underwent 3350 IVF cycles with fresh embryos over a period of 4 years.

Endometrial thickness is still a part of standard cycle monitoring during IVF but lacks robust evidence in its favor as a potential predictor of live births and success rate of the cycle.

Endocrine profile is being increasingly used in infertility practice to predict the outcome of various ART techniques.

Multivariate regression analysis showed that EMT was non-linearly associated with live birth rates.

Thickness between 7.0 mm and 9.0 mm resulted in about 30% live birth rate while thickness less than 7.0 mm was associated with only 22% live birth rate and a decrease in neonatal birth weight.

The results of the study reaffirm the value of measuring EMT as a prognostic tool for predicting live birth rates and neonatal weights in women undergoing IVF with fresh embryo transfer along with endocrine profile in late follicular phase.

2 comments:

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