Sunday, June 4, 2017

The final frontier in infertility treatment: 3-D printed ovaries produce healthy offspring


courtesy: panorama.com
The brave new frontier of Organ Printing will not be a Sci-Fi fiction but will soon be a reality for Medical field. Every year about 120,000 organs are transplanted from human donor to recipient, including donor and cadaver transplant.

But, there is always organ shortage as evident by long waiting list for transplant and many times people die because of unavailability of suitable match.

Imagine what it would be like to give command ‘Print’ and the organ will be ready. As yet, such bioprinting is still in experimental stage, currently bio-printed tissue is only used for drug testing but researchers are hopeful that it will be available for transplant in few years.

Researchers have implanted printed muscles, bones and ears in animals and were successful in integrating them flawlessly with the recipient.

Taking a leap forward in this direction researchers at Northwestern University FeinbergSchool of Medicine and McCormick School of Engineering have bioprinted ovaries that are functioning normally.

They removed a mouse ovary and replacing it with a bioprosthetic ovary, the mouse was not only able to ovulate but also give birth to healthy pups and nurse them.

The paper was published on May 16, in Nature Communications.

Teresa K. Woodruff, a reproductive scientist and director of the Women’s Health Research Institute at Feinberg said, “This research shows these bioprosthetic ovaries have long-term, durable function, using bioengineering, instead of transplanting from a cadaver, to create organ structures that function and restore the health of that tissue for that person, is the holy grail of bioengineering for regenerative medicine.”

This will have huge impact on humans, to restore fertility and hormone production in women who have undergone adult cancer treatments or those who survived childhood cancer and now have increased risks of infertility and hormone-based developmental issues.

The Full-text of the article in Nature Communications can be accessed here.  

                               3-D printed ovaries produce healthy offspring



7 comments:

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