Ovarian conservation
at hysterectomy does not reduce the risk of future cardiometabolic diseases
reports the results of large prospective cohort study published in Menopause,
the journal of The North American Menopause Society (NAMS).
This is one
of the few studies that focuses on long term effect of hysterectomy with
ovarian conservation. Earlier studies have documented strong evidence between increased
incidence of cardiovascular diseases(CVD) and other chronic diseases after hysterectomy
with bilateral oophorectomy.
The risk was
especially increased if the hysterectomy was carried out before the age of 35.
Using
Epidemiological project record, the researchers identified 2094 women who underwent
hysterectomy with ovarian conservation between 1980 and 2002. Each woman was
age matched with a control residing in the same county and who have neither
undergone hysterectomy nor bilateral oophorectomy.
Cox
proportional hazard models and Kaplan-Meier analysis was used to calculate hazards
ratios and absolute risk after taking into consideration 20 risks factors and
other potential confounders.
The two cohort
were followed up for a period of 22 years, and women who have undergone
hysterectomy were at increased risk of obesity, hyperlipidemia, hypertension,
cardiac arrhythmias and coronary artery diseases.
Women who
had hysterectomy under the age of 35 years were at nearly 5 times increased risk
of congestive heart failure and 2.5 times increased risks of coronary artery
disease.
Dr. JoAnn
Pinkerton, NAMS executive director said in a NAMS press release, “These study
results suggest that alternative uterine-preserving treatments may need to be
considered more often in lieu of hysterectomies, especially in benign
situations. For those women having hysterectomy, hormone therapy should be
considered for added protection, because ovarian function appears to be
impaired by the surgery.”
Media courtesy:
Detroit Free Press
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