Monday, January 30, 2017

Mother’s Cervicovaginal microbiota could be the key to prevent Spontaneous Preterm Births--News from SMFM 2017, Las Vegas.

Courtesy: CDC

More exciting news from the pregnancy meeting, SMFM 2017, Las Vegas. Researchers have identified that maternal cervicovaginal (CV) flora plays an important role in timing of delivery, it could increase or prevent the risk of Spontaneous Preterm Births (SPTB).  

The study abstract was presented on January 26,2017 at the meeting and won the March of Dimes award for best abstract on prematurity.

This was a nested study of a large project called as “Motherhood and the Microbiome” that was funded by National Institute of Nursing Research (NINR). This is a large observational, prospective study of women with a term birth undergoing follow up for Preterm Births.

Dr. Elovitz, professor of Obstetrics and Gynecology at the University of Pennsylvania, vice chair of Translational Research and Director of the Maternal and Child Health Research Center at PENN University and his colleagues worked on the hypothesis that preterm birth occurs because of some changes at molecular, anatomical and microbial level in the cervicovaginal space that are different in women who have a SPTB vs. women who deliver at term.

The study recruited about 1500 patients and collected cervicovaginal specimens at 3 time points throughout pregnancy. From this larger pool of participants, 80 cases with SPTB and 320 term controls were matched and analyzed. 16S rRNA gene analyses was used to identify bacterial specimens.

Additionally, in 616 patients single sample was collected to serve as validation.

Presence of Bifidobacterium species in the cervicovaginal space was highly protective for SPTB at all time while BV-associated bacteria (BVABs) and Mobiluncus were associated with statistically significant rise in SPTBs. (p<0.0001).

Edward R.B. McCabe, MD, PhD, senior vice president and chief medical officer of the March of Dimes said “From these data, we may learn how to prevent preterm birth either by eliminating the CV bacteria that are associated with an increased risk and/or by enhancing the presence of protective bacteria. This is a promising new area that should become a research priority.”



15 comments:

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  9. I am so happy, i never believe i will be this happy again in life, I was working as an air-hoster ( cabby crew ) for 3years but early this year, i loose my job because of this deadly disease called Herpes virus (HSV), I never felt sick or have any symptom, till all workers were ask to bring their doctors report, that was how i got tested and i found out that am HSV positive that make me loose my job, because it was consider as an STD and is incurable disease, i was so depress was thinking of committing suicide, till i explain to a friend of mine, who always said to me a problem share is a problem solved, that was how she directed me to Dr Isibor, that was how i contacted him and get the medication from this doctor and i got cured for real, I just went back to my work and they also carry out the test to be real sure and i was negative. Please contact this doctor if you are herpes positive  diseases his email is: drisiborspellhome@gmail.com 
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  10. Can't still believe that i got cured from Genital Herpes through herbal treatment from Dr LUCKY who I met through the internet, I actually couldn't believe it at first because it sounded impossible to me knowing how far I have gone just to get rid of it. Dr LUCKY send me his medicine which I took as instructed and here I am living a happy life once again, a big thanks to Dr LUCKY , I am sure there are many herbal doctors out there but Dr LUCKY did it for me, contact him on Email him; { drluckyherbalcure@gmail.com }

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  11. i visited different hospital but they gave me list of expensive drugs to treat the symptoms and never cured me. A closed friend of mine introduce me to a Herbal Doctor who cured her. I was scared to contact him because of what i experienced from fake doctors. she encouraged me and gave me his whatsapp contact,and i contacted him and i asked him series of questions, i also ask him to show me the results of those he have cured with his herbal drugs,and he gave me all the information i needed that gave me hope. He send a Herbal medicine to me that i took and it seriously worked for me. am now Hepatitis negative. God bless you for being a sincere and great man. Am so excited and am free from herpes virus. you can reach him via email;dralikaherbalhome@gmail.com or whats-app/call on +2348116570358.

    ReplyDelete
  12. I am so happy, i never believe i will be this happy again in life, I was working as an air-hoster ( cabby crew ) for 3years but early this year, i loose my job because of this deadly disease called Herpes virus (HSV), I never felt sick or have any symptom, till all workers were ask to bring their doctors report, that was how i got tested and i found out that am HSV positive that make me loose my job, because it was consider as an STD and is incurable disease, i was so depress was thinking of committing suicide, till i explain to a friend of mine, who always said to me a problem share is a problem solved, that was how she directed me to Dr Isibor, that was how i contacted him and get the medication from this doctor and i got cured for real, I just went back to my work and they also carry out the test to be real sure and i was negative. Please contact this doctor if you are herpes positive  diseases his email is: drisiborspellhome@gmail.com 
    or his WhatApp contact +2348110493039

    ReplyDelete
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