Tuesday, June 14, 2016

Power of Vaccinations in pregnancy.

Vaccinating pregnant women serves the dual purpose of protecting the women as well as her unborn child. Maternal immunization has emerged as a successful strategy to transfer immunity to unborn child and preventing many unnecessary deaths.

United Nations Millennium Development Goals includes reducing maternal and neonatal mortality by reducing vaccine preventable diseases as one of its important goal.

An e-poster during the 2016 ACOG clinical meeting dealt with the clinical importance of increasing acceptance for vaccination during pregnancy.

Dr. Emmie Strassberg from the Geisinger Health System in Danville, Pennsylvania presented results of a survey which showed that the rate of acceptance for the influenza vaccination was 70.1%, compared with 76.3% for the Tdap vaccination.

The study also showed that physician recommendation was the strongest predictor for Tdap vaccine acceptance (P<.001) and educational material distributed among patient increases the influenza vaccine acceptance (P<.001).

Specific Vaccinations in pregnancy depends on age, lifestyle, medical conditions you may have, such as asthma or diabetes, type and locations of travel, and previous vaccinations.

It is advocated that physicians and patients should make sure that the immunizations are up to date before planning to become pregnant.

Vaccines Before Pregnancy

Most women are vaccinated with MMR in childhood but it is better to confirm. If you need to be vaccinated with Rubella, you should avoid pregnancy for at least a month and ideally till you confirm your immunity by a blood test.

Vaccines During  Pregnancy

Whooping Cough: (Pertussis) is one of the most common vaccine preventable disease. According to CDC all pregnant women should receive a dose of Tdap during each pregnancy, preferably at 27 through 36 weeks. In addition, all family members and caregivers (like babysitters or grandparents) of infants should also get vaccinated with Tdap. After delivery once the baby is 2 months old he should get his pertussis vaccine as recommended by pediatrician.

In June 2013, ACOG weighed in on this issue in a Committee Opinion (#566) from its Committee on Obstetric Practice, agreeing on the importance of a Tdap vaccination for pregnant women due to the safety concerns about pertussis. 

Flu: Pregnant women who get flu, can have serious complications like premature labor, babies that are small for gestational age, hospitalization, and, rarely, death. A woman can be vaccinated with the inactivated flu vaccine at any time during any trimester. The Centers for Disease Control and Prevention (CDC) affirms that pregnant women who get vaccinated for the flu not only receive protection personally but also so do their babies for up to 6 months after their birth. In addition, everyone who cares for the baby should also be vaccinated.


Hepatitis B vaccine:  All pregnant women should be screened for hepatitis B. If she tested negative than vaccination can be considered if she is high risk for the infection. A series of three doses is required to have immunity. The 2nd and 3rd doses are given 1 and 6 months after the first dose. If she tests positive for the disease, then the baby should receive within 12 hours of birth first dose for vaccine and Hepatitis B immunoglobulin (HBIG).


Other vaccines:  Some women may need other vaccines like Hepatitis A and meningococcal vaccine depending upon the life style and travel requirements. These can be administered when needed.


Travel vaccines: Depending on your destination you could need additional vaccines. However, there are some vaccines that should be avoided during pregnancy, so it's best to weigh the risks and benefits of vaccination based on your destination.


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