EXPLORER, the world’s first whole-body PET/CT scanner has produced some amazing human images, opening doors to numerous diagnostic and therapeutic applications in the future. The first human images by the scanner were shown at the Radiological Society of North America annual meeting, Nov. 24- Nov. 30 in Chicago.
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Simon Cherry
and Ramsey Badawi
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A brainchild of UC Davis scientists Simon Cherry and Ramsey Badawi, the EXPLORER combines positron emission tomography (PET) and X-ray computed tomography (CT) making it possible to image the whole body at the same time. The scanner has been developed in partnership with Shanghai-based United Imaging Healthcare (UIH), which built the system based on its latest technology platform and will eventually manufacture the devices for the broader health care market.
Researchers say that the machine captures radiation far more efficiently than any other scanner, producing images in as little as 1 second and, over time, produce videos that can track the journey of specially tagged drugs through our entire body.
EXPLORER is 40 times faster than current PET scanners and can produce images of whole-body in as little as 20 to 30 seconds. The radiation dose can be further reduced at the expense of a few extra seconds under the scanner or if needed a longer scan at the standard dose will produce optimal image quality.
“The tradeoff between image quality, acquisition time and injected radiation dose will vary for different applications, but in all cases, we can scan better, faster or with less radiation dose, or some combination of these,” Cherry said.
It is for the first time that a scanner can visualize simultaneously that what is happening at the organ as well as tissue level. It will also benefit patients and physician by documenting the spread of cancer, inflammation in body tissues, various infection, immunological and metabolic disorders and much more.
“I don’t think it will be long before we see at a number of EXPLORER systems around the world,” said Cherry and is very optimistic about the future of the EXPLORER.
The UC Davis team is working closely with UIH to get the first system installed in Sacramento, USA, and the first system is expected to begin imaging patients as early as June 2019.
Here’s a scan of a whole body taken using the EXPLORER



