Showing posts with label Magseed. Show all posts
Showing posts with label Magseed. Show all posts

Sunday, September 24, 2017

Today is World Cancer Research Day: A call to action by ASCO- Don’t Stand Still. We Won’t


September 24th is  World Cancer Research Day. American Society of Clinical Oncology (ASCO)calls upon to continue and heighten research in areas of cancer prevention and treatment, along with discovering new drugs. World Cancer Research Day is a global initiative that aims to raise awareness about the critical importance of cancer research.

It is estimated that by 2030 cancer will be the leading cause of death worldwide with new cases expected to increase to 21.6 million each year. According to the GLOBOCAN report, in 2012 there were 14 million new cases diagnosed and 8.2 million cancer-related deaths worldwide.

Life years and productivity loss, together with disabilities resulting from cancer account for the largest economic cost on a global scale, compared to other causes of death including infectious diseases.

One of the most important areas is to support and promote research on the causes, prevention and early detection of cancer as a key element in controlling the disease. This will lead us towards the discovery of a cure for cancer or transforming the disease into a chronic illness, both approaches translating into higher survival rates.

Some of the important research paper on Obstetrics and Gynecological cancer published recently are:

USPSTF simplifies cervical cancer screening recommendations: Dual testing no longer advised
The US Preventive Services Task Force (USPSTF) has issued new draft recommendations for cervical cancer screening with a major change that it recommends either cervical cytology (CC) or high-risk HPV (hrHPV) test as a screening procedure every 3 years for women aged 30-65 years, and not both ( Grade A)  

Magseed, a minimally invasive breast marker for cancer localization during surgery receives clearance in Europe
Endomag, a surgical guidance company received CE clearance for Sentimag+Magseed breast cancer diagnostic system, that guides surgeon for precise location of impalpable tumor during breast lumpectomy. It improves outcome and reduces the amount of radioactive exposure for patients.

FDA clears first 2D digital mammography system that allows patients to control the compression
GE Healthcare announced today FDA 510(k) clearance of an industry-first, patient-assisted mammography system, Senographe Pristina Duetathat makes mammography experience more comfortable by putting the control in patients’ own hands.

FDA approves world’s first pioneering gene therapy for cancer
The U.S.Food and Drug Administration in its landmark and historic action today approved the world’s first gene therapy, Novartis' Kymriah (tisagenlecleucel) for certain pediatric and young adult patients with a form of acute lymphoblastic leukemia (ALL).

This opens a new frontier in treatment of cancer and other serious and life-threatening diseases.

Are you dense? What every woman and her healthcare provider needs to know.
Nearly 20 plus years of research have provided sufficient evidence to link dense breast tissue and increased risk of missing cancer diagnosis by screening mammography. As the breast density increases, the reliability of mammogram as a screening tool for picking up breast malignancy decreases.
What is meant by “being dense”? Breast density does not correlate with physically palpated firmness of breast, it is a radiologic finding and cannot be predicted without obtaining a mammogram. 

Now Ovarian Tissue paper to support normal hormonal production: Breakthrough in Regenerative Medicine
An accidental Spill has sparked a breakthrough in the field of regenerative medidicne. Scientists and engineers at the Northwestern Medicine have invented a range of bioactive “tissue papers” made from organs combined with a polymer to make them so pliable.

These new “tissue papers” are so thin and pliable that they can be folded into an origami bird. Their clinical application is for wound healing and aid in natural hormone production in young cancer patients.

Adjunct Metformin helps reversal of atypical endometrial hyperplasia
Adjunct metformin treatment help reversal of atypical endometrial hyperplasia (AEH) and improves overall survival in endometrial cancer reports the result of a systematic review and meta-analysis published ahead of print in Journal of Gynecologic Oncology.

FDA Approves PARP inhibitor Zejula for treatment of recurrent ovarian cancer.
The U.S.Food and Drug Administration today approved Zejula (niraparib) for the maintenance treatment of epithelial ovarian, fallopian tube or primary peritoneal cancer in adult patients who have already responded well to platinum-based chemotherapy.

Here is an interesting video about importance of research on World Cancer Research Day 2017







Friday, September 15, 2017

Magseed, a minimally invasive breast marker for cancer localization during surgery receives clearance in Europe



Endomag, a surgical guidance company received CE clearance for Sentimag+Magseed breast cancer diagnostic system, that guides surgeon for precise location of impalpable tumor during breast lumpectomy. It improves outcome and reduces the amount of radioactive exposure for patients.

As breast cancer screening techniques increases, the tumors are now detected at very early stages, when they are smaller, difficult to locate and less well defined. Nearly 50% of all tumors are not palpable at diagnosis and also not well delineated during the surgery.



Magseed allows for precise localization of lump during surgery. It is placed in place by radiologist under mammo or tomo guidance, it is smaller than a grain of rice, takes only minutes for placement and cannot be dislodged from the site for 30 days. The patient can go on with her life with no discomfort.

On the day of surgery, the surgeon uses the Sentimag to accurately locate the tumor before making an incision thereby ensuring complete removal of tumor, better cosmetic outcome and less surgical time. Sentimag is essentially a highly sensitive magnetometer that is able to spot the implanted Magseed without exposing patient to radiations.

X-ray showing a complete surgical specimen with negative margins and Magseed™ in the centre, next to the cancer.

The Magseed is safe in MRI environments and can also be spotted by USG.

Traditional guide wires, which were inserted by a radiologist in earlier times, are source of constant discomfort as they protrude from a patient's breast restricting the patient to the hospital. In 25%  of cases they are displaced before performing  surgery which calls for additional follow up surgeries as the cancerous tissue is left behind.

In USA, the Magseed device was FDA 510(k) cleared in March 2016 and since been adopted across many hospitals.

Magseed –Safety and feasibility study of the use of magnetic marker seeds to localize breast cancers” was published in May 2017 in European Journal of Surgical Oncology (EJSO).

Eric Mayes, CEO Endomag: “After the successful launch of Magseed in the US, where many of the top cancer centers are now using it routinely, we couldn’t wait to make it available across Europe. Sysmex’s experience with the Sentimag and Sienna system makes it an ideal partner for Magseed, and Sysmex has demonstrated its ability to successfully launch and grow sales of our products across the EMEA region. Together, we can now offer the first radiation-free surgical guidance platform for both lesion localization and sentinel node biopsy using a single instrument.”

The Sentimag+ Magseed system has been installed in 130 hospitals across EMEA countries and been used in over 25,000 breast cancer operations.

                               Here is a video about Magseed.