Showing posts with label ASRM 2017. Show all posts
Showing posts with label ASRM 2017. Show all posts

Wednesday, November 1, 2017

News from ASRM 2017: Yoga helps to improve the outcome in infertility patients


Two papers presented here today at the at the American Society for Reproductive Medicine’s Scientific Congress in San Antonio (ASRM 2017) highlighted the importance of yoga in patients undergoing infertility treatments.

It is known that stress negatively affects reproductive outcome in ARTs and Yoga help improve the pregnancy rate and reduce the anxiety levels as an adjuvant treatment during the period.

Both the papers were also published in Fertility and Sterility September supplement.


A team of researchers from a private clinic in New Delhi examined the impact of Yoga on pregnancy rates for women who had already undergone one unsuccessful IVF treatment with fresh embryos.
Women with more than 5 years of subfertility, less than 38 years of age with no anatomical uterine anomalies were randomized to receive (n=105) either 30 sessions of Yoga over a period of 3 months, including asana (exercises) and pranayama (regulated breathing) followed by frozen embryo transfer or to have the embryo transfer in subsequent month(n=53) without any yoga sessions.

All women in the Yoga group completed Hamilton Depression Rating Scale (HAM- D), Hamilton Anxiety Rating Scale (HAM-A) and FertiQol questionnaire at baseline (S1) and after 3 months of YOGA sessions (S2) to assess the anxiety scores.

Following embryo transfer, 63% of the women in the yoga group achieved pregnancy as compared with 43% in the group with no Yoga training (P = 0.039). There was also remarkable improvement in the psychological wellbeing in women who had the yoga training.

The team from Chicago investigated the efficacy of attending an on-line or in person yoga class in bringing down the stress and anxiety levels in women with previous failed IVF.

In this small prospective cohort study of 26 patients, women were allowed to enroll into in person or an online yoga class for about 6 sessions. Spielberger State-Trait Anxiety Inventory (STAI) were completed before and after the intervention.

A significant decrease in anxiety and stress was observed in both the groups, which furthers the idea that an online yoga teaching is also equally effective as in person.
The study is still ongoing and recruiting participants, and the additional data will help strengthen the previous results.

We know infertility patients suffer from very high stress levels. These studies show that yoga represents a promising therapy for reducing patient stress during infertility treatment and even potentially improve outcome of such treatment,” said Richard J. Paulson, MD, President of the ASRM in a news release.



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Monday, October 30, 2017

News from ASRM 2017: Subfertility May be Harbinger of Disease Later in Life


The American Society for Reproductive Medicine (ASRM) 2017 Scientific Congress kicked of today morning by an opening keynote address from President Richard J. Paulson, M.D. at San Antonio, TX. The agenda ranges from the latest molecular and genetic technologies to advocacy for the patients with a focus on access to care.

Researchers from the University of Pennsylvania today presented research showing that women seeking infertility treatment have a shorter life span as compared to their parous counterparts. They have a higher risk of dying from endocrine related disorders such as diabetes and breast cancer than other women.

This retrospective cohort study examined  records of nearly 80,000 women and followed them for nearly 13 years, with an aim to determine the association of a history of infertility with all-cause mortality.

These women were enrolled in the Prostate Lung, Colorectal, and Ovarian (PLCO) Cancer screening trial from 1992-2001. Nearly 76,000 women had data on infertility.

It was seen that 14.5% (n=11,006) of women did not have any children. The average age at death for each cohort was similar (74 years) but women in infertile cohort had 10% greater chances of dying as compared to fertile cohort.  (HR1.10, 95%CI 1.03, 1.17, p=0.005).

Infertile women also face 69% increased chances of dying due to diabetes, 49% more chances of death due to breast cancer.

Ovarian cancer and Endometrial cancer did not increase the risk of death, although infertile women had marginally high risk of ovarian cancer.

This large retrospective study does show an association between endocrine related diseases and infertility but does not prove causation.It stresses the need of prospective studies and more research  in this area.

But, infertility can present an early opportunity to screen these women for chronic diseases and interventions.

Richard J. Paulson, MD, President of ASRM said in a News Release, “This is an intriguing and potentially very important study. More work is clearly needed to help us understand if, in some patients, there might be an underlying medical problem that presents as infertility during the reproductive years and then contributes to endocrine-related disease later in life. We also need to investigate if infertility treatments can counter some of this increased risk.”

The study is also published in Fertility and Sterility September supplement.